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01/05/09 - 7:46 PM CST


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Click on the link below to be connected to the Stroke Trials Directory,* a continuously updated registry of randomized clinical trials. This project is a joint effort of the Internet Stroke Center at the Washington University School of Medicine, the American Stroke Association, and the National Institute of Neurological Disorders and Stroke. A key to the acronyms of ongoing trials in stroke is also provided below.

*Stroke Trials Directory is an independent site which does not receive pharmaceutical industry support

The Internet Stroke Center, Stroke Trials Directory* - Click Here

  • ARCH, Aortic Arch Related Cerebral Hazard
  • CAPRIE, Clopidogrel vs. Aspirin in Patients at Risk of Ischemic Events
  • CHARISMA, Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance
  • CREST, Carotid Revascularization Endarterectomy vs Stent Trial
  • ESPRIT, European / Australasian Stroke Prevention in Reversible Ischaemia Trial
  • FASTER, Fast Assessment of Stroke and Transient ischemic attack to prevent Early Recurrence
  • MATCH, Management of Atherosclerosis and Thrombosis with Clopidogrel in High-risk Patients with Recent TIA or Ischemic Stroke
  • PRoFESS, Prevention Regimen For Effectively avoiding Second Strokes
  • SPARCL, Stroke Prevention by Aggressive Reduction in Cholesterol Levels
  • SPS3, Secondary Prevention of Small Subcortical Strokes Pilot Study

American Stroke Association (ASA):

  1. Early Management of Patients With Ischemic Stroke
    http://stroke.ahajournals.org/cgi/reprint/34/4/1056.pdf
  2. Primary Prevention of Ischemic Stroke
    http://stroke.ahajournals.org/cgi/reprint/37/6/1583
  3. Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack
    http://stroke.ahajournals.org/cgi/reprint/37/2/577

American College of Chest Physicians:
Sixth ACCP Consensus Conference on Antithrombotic Therapy
http://www.chestjournal.org/cgi/reprint/119/1_suppl/1S.pdf

National Stroke Association (NSA):
http://jama.ama-assn.org/cgi/reprint/281/12/1112

American Academy of Neurology (AAN):

  1. Anticoagulant and antiplatelet agents in acute ischemic stroke
    http://www.aan.com/professionals/practice/pdfs/gl0097.pdf
  2. Stroke prevention in patients with non-valvular atrial fibrillation
    http://www.aan.com/professionals/practice/pdfs/gl0017.pdf
  3. Thrombolytic therapy for acute ischemic stroke
    http://www.aan.com/professionals/practice/pdfs/gl0025.pdf